脑膜炎奈瑟球菌(Neisseria meningitides)

简介

    脑膜炎奈瑟球菌(Neisseria meningitides)属于奈瑟菌科(Neisseriaceae)。需氧，革兰阴性双球菌、苛养、产荚膜，初次分离在5-10%CO2环境生长更好

临床相关性

       主要引起儿童脑膜炎和败血症，可定植于健康成人鼻咽部。至少有12种血清型，95%的感染由A、B、C、X、W 或Y群血清型引起。随着疫苗的广泛接种，发病率明显降低。也可引起其它各种感染，如心内膜炎、肺炎、泌尿生殖道感染、关节炎、腹膜炎等等。

药敏

         KB法检测药敏纸片直径或微量肉汤稀释法检测MIC，受试抗生素折点参考M100ED33 Table2I（2023版）。

参考文献

1.Hollingshead S,et al. An Overview of Neisseria meningitidis.Methods Mol Biol.2019;1969:1-16.

2.Feldman C,et al.Meningococcal pneumonia: a review. Pneumonia(Nathan).2019Aug 25;11:3.

3.Bazan JA,et al.Emergence of a novel urogenital-tropic Neisseria meningitidis.Curr Opin Infect Dis.2021Feb1;34(1):34-39.

4.Longo B,et al.Primary septic arthritis of the knee caused by Neisseria meningitidis serogroup B in an elderly patient. Case report and review of the literature. Infection.2023 Apr;51(2):499-506

5.Ali M,et al. Neisseria meningitidis endocarditis: a case report and review of the literature. Scand JInfect Dis.2011 Sep;43(9):747-9.

6.Kleinpeter MA,et al.Neisseria meningitidis peritonitis in a CAPD patient: first case report and review of the literature. Adv Perit Dial.1995;11:168-71.