牛棒状杆菌(Corynebacterium bovis)

简介

      牛棒状杆菌(Corynebacterium bovis)属于棒状杆菌科(Corynebacteriaceae)，需氧革兰阳性多形杆菌，如拟球形（coccoid）、棒状（ club-shaped )。

临床相关性

       主要引起牛乳腺炎、肾盂肾炎等。可引起人败血症、肾炎、脑膜炎、腿部溃疡、慢性中耳炎、硬膜外脓肿、心内膜炎、人工关节感染、眼部感染等。

药敏试验

       肉汤稀释法（裂解马血阳离子调节肉汤）检测MIC，受试抗生素及其折点参考M45ED3 Table6；β-内酰胺类抗生素结果须孵育48小时后观察，其余抗生素如24小时培养后生长孔生长明显则可以判读结果。培养中遇到棒杆菌通常认为是污染菌。对分离自无菌部位标本（如深部组织，脑脊液，多套阳性血培养）植入假体装置，来自免疫缺陷患者的菌株需要药敏试验；KB法实验方法及折点信息参考EUCAST相关折点表.

参考文献

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